Product limits
Critical product temperature, concentration, fill depth, residual moisture and acceptable cake appearance.
Pharmaceutical lyophilizers
Pharmaceutical Lyophilizers for Vials, Biologics & Diagnostics
Review published SSLY shelf-area and water-capture references, then align container format, batch definition, product limits, no-load shelf conditions, utilities and documentation before selecting a configuration.
1–40 m²Published shelf-area range
20–400 kgReference water capture for listed models
−50 to +70°CNo-load shelf temperature reference
≤5 PaUltimate-vacuum reference
Selection worksheet
Choose a configuration around the product, container and batch.
Share these inputs so shelf area, water capture, loading and facility requirements can be reviewed together.
Container count
Vial diameter and height, fill volume, stopper format, units per batch and loading pattern.
Cycle basis
Freezing approach, primary- and secondary-drying targets, known cycle basis and endpoint method.
Facility boundary
Room classification, door orientation, technical-area access, material flow and maintenance clearances.
Automation level
Loading and stoppering method, recipe handling, audit functions and plant-system interfaces.
Project evidence
Required drawings, material records, FAT scope, calibration, training and qualification responsibilities.
Published model data
Published SSLY references for model comparison.
Use these published references for an initial comparison. Final performance, utilities and document scope are confirmed in the project quotation.
| Model | Shelf area | Water capture / batch | Shelf structure | Shelf temperature* | Cold trap* | Ultimate vacuum* |
|---|---|---|---|---|---|---|
| SSLY-1 | 1 m² | 20 kg | 4+1 shelves | −50 to +70°C | ≤−70°C | ≤5 Pa |
| SSLY-10 | 10 m² | 200 kg | 7+1 shelves | −50 to +70°C | ≤−70°C | ≤5 Pa |
| SSLY-20 | 20 m² | 400 kg | 14+1 shelves | −50 to +70°C | Configuration-dependent | ≤5 Pa |
| SSLY-40 | 40 m² family | Confirm in proposal | Project-specific | Confirm in proposal | Confirm in proposal | Confirm in proposal |
* No-load published values. The 20–400 kg figures are listed-model water-capture references, not product or fresh-load capacity. Product temperature, drying rate and batch performance depend on the product, recipe, loading and operating conditions.
Process-critical controls
Review the controls that shape the product result.
Review these items with the process, production and quality teams before fixing the equipment scope.
Freezing
Product structure begins hereReview shelf cooling, nucleation assumptions, fill depth and the temperature margin before primary drying.
- Shelf ramp and hold control
- Product probes by agreed scope
- Uniform loading pattern
Primary drying
Balance heat input and vapour flowChamber pressure, shelf temperature, condenser capacity and product temperature must remain within the process window.
- Vacuum-control strategy
- Condenser margin
- Endpoint method
Secondary drying
Reach the moisture targetControlled heating and hold time support desorption without exceeding the product temperature limit.
- Recipe repeatability
- Trend and alarm review
- Stoppering sequence
Utilities & interfaces
List the room and utility inputs before the proposal.
Model, cycle and site conditions determine the final requirements. Bring the available utilities, room interfaces and responsibility split to the review.
ElectricalVoltage, frequency, connected load and control power
CoolingWater or air-cooled basis, inlet conditions and heat
rejection
Compressed airInstrument-air quality, pressure and consumption if
required
Cleaning / sterilisationWater, steam, drainage and exhaust by agreed CIP / SIP
scope
Room interfacesCleanroom door, technical area, exhaust, drainage and
access
DataUser roles, recipes, alarms, trends, audit functions and
network boundary
Project deliverables
Agree the project documents and handover scope.
The final list is agreed for the project. Use these items to make the review concrete before manufacture, FAT and installation.
Before manufacturing
- Approved configuration and interface responsibilities
- General arrangement and interface drawings
- Utility schedule and site-readiness inputs
- Controls and documentation scope
Before shipment
- Agreed FAT protocol and records
- Inspection and calibration records by scope
- Equipment, component and packing records
- Open-item and change-control list
At installation
- Installation and commissioning guidance
- Operation and maintenance manuals
- Operator and maintenance training
- Recommended spare-parts list
Actual equipment
Review the configuration with application, facility and procurement teams.
A useful review combines the formulation or process brief, production target, facility inputs, quality expectations and procurement scope—not model data alone.
Send the six selection inputsFAQ
Questions buyers ask before selection.
Short answers support early evaluation; project-specific decisions remain subject to engineering confirmation.
Which SSLY model is suitable for a pilot or production project?
Selection depends on container format, units per batch, shelf area, listed-model water-capture reference, loading method, utilities and documentation scope. A model code should follow this engineering review; the 20–400 kg values for listed models are not product or fresh-load capacity.
Can the system include hydraulic stoppering?
The published SSLY range includes common and hydraulic stoppering configurations. The mechanism, pressure and applicable container system must be confirmed in the technical proposal.
What temperature and vacuum values are published?
Selected published SSLY data lists a no-load shelf setting range of −50°C to +70°C and ultimate vacuum of ≤5 Pa. Product performance and cycle conditions remain project-specific.
Can the system integrate with cleanroom loading and plant utilities?
Door arrangement, technical-area access, material flow, utilities, controls and documentation can be reviewed within the project scope. The final interface list and responsibilities are confirmed for the site and proposal.